Inclusion criteria for patients in this study were: (1) non manipulated HLA-genoidentical sibling HSCT performed in Hôpital Saint Louis from January 1994 to August 1999, (2) patients with de novo ...

Highly active anti-retroviral therapy (HAART) is the standard of care for HIV infection; however, pharmacogenomic approaches highlighted significant interindividual differences in drug disposition, ...

Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized ...

Pharmacogenetics investigates the relationship be-tween genetic factors and responses to drugs in various ethnic groups. These differing responses are caused by polymorphisms -- tiny differences in ...

(HealthDay News) – For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity, according to a study published in the ...

(HealthDay News) – The functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene is associated with increased risk of cardiovascular disease mortality and morbidity, ...

You say the antibiotic that cured your best friend's bladder infection made you break out in a full body rash? And the hormone therapy they used to shrink your father's prostate cancer made it grow ...

Representation of three different types of platforms for ionic liquid-based drug development to deliver poorly soluble compounds--Courtesy of Russian Academy of Sciences A new way to develop drugs may ...

Adjuvant chemotherapy cures only a subset of women with nonmetastatic breast cancer. Genotypes in drug-metabolizing enzymes, including functional polymorphisms in cytochrome P450 (CYP) and glutathione ...