Scientists have created a 6-legged mouse embryo with an extra pair of hindlimbs at the expense of their external genitalia. But far from creating a monster, this rudimentary rodent provides important ...
Magdalena (Magda) Zernicka-Goetz, today a developmental and stem cell biologist at the University of Cambridge and California Institute of Technology, recalled being an artistic child who enjoyed ...
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Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development
A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...
Study reveals that genomic nuclear speckle-associated domains (SPADs) are step-wise organized during mouse early embryogenesis, with key factors contribution in this process. Following mammalian ...
Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found ...
Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...
Metabolism does more than fuel embryos—it sets their developmental rhythm. EMBL researchers found that a sugar molecule, FBP, controls the pace of spine formation, suggesting metabolism may act as a ...
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