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Multimedia Tools and Applications publishes original research on multimedia development and system support tools as well as case studies of multimedia ...
MTAP loss: a possible therapeutic approach for glioblastoma
Dec 26, 2022 · In this article, we review the loss of the 5′-methylthioadenosine phosphorylase (MTAP) gene as a potential therapeutic approach for treating glioblastoma. MTAP encodes a …
Volumes and issues | Multimedia Tools and Applications - Springer
Multimedia Tools and Applications publishes original research on multimedia development and system support tools as well as case studies of multimedia ...
Mesothelioma: molecular pathology and biomarkers
Aug 7, 2024 · While BAP1, as mentioned above, can aid in distinguishing mesothelioma from lung carcinoma, aberrant MTAP and/or merlin staining can be seen in other malignancies and is …
Mesothelioma: morphologic and immunohistochemical findings
Apr 3, 2024 · Mesothelioma in situ is now recognized as either a single layer of bland cuboidal mesothelial cells that have lost BAP1, and sometimes MTAP, on immunohistochemical …
Reduced symmetric dimethylation stabilizes vimentin and …
Jun 29, 2022 · Utilizing our invasive cell‐based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and …
Assessment of CDKN2A homozygous and heterozygous deletions …
Jun 5, 2025 · The evaluation by IHC-MTAP and IHC-p16 was performed by two neuropathologists who were initially blinded to the histological diagnosis or molecular CDKN2A status. Staining …
Loss of methylthioadenosine phosphorylase immunoreactivity …
Apr 1, 2024 · To ascertain MTAP status as an independent prognostic factor, we first employed univariate analysis of several key clinical variables and MTAP status for the impact on PFS …
Aims and scope | Multimedia Tools and Applications - Springer
Multimedia Tools and Applications publishes original research articles on multimedia development and system support tools, and case studies of multimedia applications. Experimental and …
Pitfalls in the evaluation of CDKN2A copy number status in
Apr 14, 2025 · Although MTAP staining offers the benefit of labeling normal cells as an internal (positive) control, our work shows that it is not always a dependable surrogate marker for …